Description Usage Arguments Details
Sets the simulation parameters for the stochastic
network model of HIV-1 Infection among Heterosexuals in
Sub-Saharan Africa for the EpiModelHIV
package.
1 2 3 4 5 6 7 8 9 10 11 12 13 | param_het(time.unit = 7, acute.stage.mult = 5, aids.stage.mult = 1,
vl.acute.topeak = 14, vl.acute.toset = 107, vl.acute.peak = 6.7,
vl.setpoint = 4.5, vl.aidsmax = 7, cond.prob = 0.09,
cond.eff = 0.78, act.rate.early = 0.362, act.rate.late = 0.197,
act.rate.cd4 = 50, acts.rand = TRUE, circ.prob.birth = 0.9,
circ.eff = 0.53, tx.elig.cd4 = 350, tx.init.cd4.mean = 120,
tx.init.cd4.sd = 40, tx.adhere.full = 0.76, tx.adhere.part = 0.5,
tx.vlsupp.time = 365/3, tx.vlsupp.level = 1.5,
tx.cd4.recrat.feml = 11.6/30, tx.cd4.recrat.male = 9.75/30,
tx.cd4.decrat.feml = 11.6/30, tx.cd4.decrat.male = 9.75/30,
tx.coverage = 0.3, tx.prev.eff = 0.96, b.rate = 0.03/365,
b.rate.method = "totpop", b.propmale = NULL, ds.exit.age = 55,
ds.rate.mult = 1, di.cd4.aids = 50, di.cd4.rate = 2/365, ...)
|
time.unit |
Unit of time relative to one day. |
acute.stage.mult |
Acute stage multiplier for increased infectiousness above impact of heightened viral load. |
aids.stage.mult |
AIDS stage multiplier for increased infectiousness in AIDS above impact of heightened viral load. |
vl.acute.topeak |
Time in weeks to peak viremia during acute infection. |
vl.acute.toset |
Time in weeks to viral set point following peak viremia. |
vl.acute.peak |
Log 10 viral load at acute peak. |
vl.setpoint |
Log 10 viral load at set point. |
vl.aidsmax |
Maximum log 10 viral load during AIDS. |
cond.prob |
Probability of condoms per act with partners. |
cond.eff |
Efficacy of condoms per act in HIV prevention. |
act.rate.early |
Daily per-partnership act rate in early disease. |
act.rate.late |
Daily per-partnership act rate in late disease. |
act.rate.cd4 |
CD4 count at which the |
acts.rand |
If |
circ.prob.birth |
Proportion of men circumcised at birth. |
circ.eff |
Efficacy of circumcision per act in HIV prevention. |
tx.elig.cd4 |
CD4 count at which a person becomes eligible for treatment. |
tx.init.cd4.mean |
Mean CD4 count at which person presents for care. |
tx.init.cd4.sd |
SD of CD4 count at which person presents for care. |
tx.adhere.full |
Proportion of people who start treatment who are fully adherent. |
tx.adhere.part |
Of the not fully adherent proportion, the percent of time they are on medication. |
tx.vlsupp.time |
Time in weeks from treatment initiation to viral suppression. |
tx.vlsupp.level |
Log 10 viral load level at suppression. |
tx.cd4.recrat.feml |
Rate of CD4 recovery under treatment for males. |
tx.cd4.recrat.male |
Rate of CD4 recovery under treatment for females. |
tx.cd4.decrat.feml |
Rate of CD4 decline under periods of non-adherence for females. |
tx.cd4.decrat.male |
Rate of CD4 decline under periods of non-adherence for males. |
tx.coverage |
Proportion of treatment-eligible persons who have initiated treatment. |
tx.prev.eff |
Proportional amount by which treatment reduces infectivity of infected partner. |
b.rate |
General entry rate per day for males and females specified. |
b.rate.method |
Method for assigning birth rates, with options of "totpop" for births as a function of the total population size, "fpop" for births as a function of the female population size, and "stgrowth" for a constant stable growth rate. |
b.propmale |
Proportion of entries assigned as male. If NULL, then set adaptively based on the proportion at time 1. |
ds.exit.age |
Age at which the age-specific ds.rate is set to 1, with NA value indicating no censoring. |
ds.rate.mult |
Simple multiplier for background death rates. |
di.cd4.aids |
CD4 count at which late-stage AIDS occurs and the risk of
mortality is governed by |
di.cd4.rate |
Mortality in late-stage AIDS after hitting a nadir CD4 of
|
... |
additional arguments to be passed into model. |
This function sets the parameters for the models.
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