PanNETsubtypesmicRNAVal: Validation of micRNA expression PanNET subtypes using miR...

Description Usage Arguments Details Value Author(s) References Examples

Description

This function selects SAM gene signature for PanNET miR expression subtypes in the validation dataset. NMF is employed to indentify PanNET subtypes in this dataset.

Usage

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PanNETsubtypesmicRNAVal(Indata, IndSAMdata)

Arguments

Indata

PanNETsubtypesmicRNAVal.Indata is the validation dataset. microRNAs are on the rows and the first column contain the microRNA names.

IndSAMdata

PanNETsubtypesmicRNAVal.IndSAMdata contain SAM micRNAs signature for finding the PanNET subtypes.

Details

The SAM gene signature in PanNETsubtypesmicRNAVal.IndSAMdata is selected from the validation dataset PanNETsubtypesmicRNAVal.Indata and NMF is employed to discover PanNET miR expression subtypes in this dataset.

Value

The output of this function include NMF micRNA expression subtypes saved in your working directory under PanNetResults/micRNAVal folder.

Author(s)

Anguraj Sadanandam anguraj.sadanandam@icr.ac.uk

References

Anguraj Sadanandam, et all (2015). A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics. Cancer Discovery.

Examples

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syspremed/PanNETassigner documentation built on May 31, 2019, 12:48 a.m.