CSSA contains a number of functions to analyze and simulation pooled CRISPR-Cas9-based screens. The simulators, represented by the CRISPRsim and sortingsim functions, offer an easy but also highly customizable tool to create data with guide- and gene-specific variables that can be randomly assigned or specified by the user. The analysis tools currently contain functions to calculate rate ratios, odds based on nonparametric guide distribution, a function to combine gene-wise Z-values or odds, and functions that calculate effect sizes of gene knockout and guide efficacy based on rate ratios and duration of the experiment.
Package details |
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Author | Jos B Poell |
Maintainer | Jos B Poell <j.poell@amsterdamumc.nl> |
License | GPL-2 |
Version | 0.1.10 |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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