tgac-vumc/CSSA: Analysis and Simulation Tools for CRISPR-Cas9 Pooled Screens

CSSA contains a number of functions to analyze and simulation pooled CRISPR-Cas9-based screens. The simulator, represented by the CRISPRsim function, offers an easy but also highly customizable tool to create data with guide- and gene-specific variables that can be randomly assigned and specified by the user. The analysis tools currently contain functions to calculate rate ratios, and a function that calculates effect sizes of gene knockout and guide efficacy based on rate ratios and duration of the experiment.

Getting started

Package details

AuthorJos B Poell
MaintainerJos B Poell <[email protected]>
LicenseGPL-2
Version0.1.2
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("tgac-vumc/CSSA")
tgac-vumc/CSSA documentation built on July 19, 2019, 4:49 a.m.