noness: Get a list of nonessential genes or corresponding indices in...

In tgac-vumc/CSSA: Analysis and Simulation Tools for CRISPR-Cas9 Pooled Screens

Get a list of nonessential genes or corresponding indices in the data set

Description

noness couples reported nonessential genes to a data set. Without arguments, it returns the list of nonessential genes. Otherwise, it returns the indices corresponding to nonessential genes.

Usage

noness(guides, genes, trnc = "_.*")

Arguments

guides	Character vector. List of guide names. Names of nonessential genes are matched to the string before what is specified in the trnc argument.
genes	Character vector. List of gene names. Names of nonessential genes are matched to the given gene names. Matches must be exact.
trnc	Character. Regular expression pattern to isolate gene name from the guide name. Default = "_.*"

Value

Returns a character vector with names of nonessential genes, or a numeric vector with indices representing nonessential genes in the given data set.

Note

The list of nonessential genes was retrieved from http://hart-lab.org/downloads.

Author(s)

Jos B. Poell

See Also

ess

tgac-vumc/CSSA documentation built on Oct. 10, 2022, 7:27 p.m.