required_events_biomarker: Calculate number of events

Description Usage Arguments Value

View source: R/calculate_numbers_of_events_continuous_variable.R

Description

#' Calculate the number of events for a continuous covariate (based on Schoenfeld's formula) Reference: "Sample-Size Calculations for the Cox Proportional Hazards Regression Model with Nonbinary Covariates" by F.Y. Hsieh, PhD, and Philip W. Lavori, PhD (2000)

Usage

1

Arguments

alpha

1-sided Alpha (Type I error)

beta

Type II error

HR

Hazard ratio associated with a one-unit change in a continuous covariate (X1)

sigma

standard deviation of the continuous covariate (X1)

Value

Number of events required


th-zelniker/TIMI documentation built on Oct. 17, 2018, 2:21 a.m.