required_events_biomarker: Calculate number of events

In th-zelniker/TIMI:

Calculate number of events

Description

#' Calculate the number of events for a continuous covariate (based on Schoenfeld's formula) Reference: "Sample-Size Calculations for the Cox Proportional Hazards Regression Model with Nonbinary Covariates" by F.Y. Hsieh, PhD, and Philip W. Lavori, PhD (2000)

Usage

required_events_biomarker(alpha, beta, HR, sigma)

Arguments

alpha	1-sided Alpha (Type I error)
beta	Type II error
HR	Hazard ratio associated with a one-unit change in a continuous covariate (X1)
sigma	standard deviation of the continuous covariate (X1)

Value

Number of events required

th-zelniker/TIMI documentation built on Oct. 1, 2022, 2 p.m.