distLRR: Find summary statistics of LRR

In thoree/mut2: Mutation stuff

Find summary statistics of LRR

Description

Finds distribution of LRR depending on allele frequencies.

Usage

distLRR(
  adjust = TRUE,
  method = "PR",
  verbose = FALSE,
  nsim = 2,
  seed = NULL,
  log2 = FALSE,
  mutMod = "equal",
  rate = c(0.005, 0.005),
  rate2 = c(1e-06, 1e-06),
  range = c(0.1, 0.1),
  nAls = 4
)

Arguments

adjust	Logical. Transform to original mutation rate
method	Transformation. See 'pedmut::makeReversible()'
verbose	Logical.
nsim	integer.
seed	Integer
log2	Logical. To get LR on log2
mutMod	character.
rate	Double. See 'pedmut::muationModel()'.
rate2	Double. See 'pedmut::muationModel()'
range	Double. See 'pedmut::muationModel()'
nAls	Integer. No of alleles.

Details

The allele frequencies are simulated uniformly. The mutation parameters are simulated uniformly between provided minimum and maximum. The LRR distribution is then calculated exactlyusing 'oneMarkerDistribution()'. The simulations are conditional on PR not failing (PR fails rarely).#'

Value

Summary of distribution of LRR, with more details if 'verbose = T'

Author(s)

Thore Egeland

Examples

distLRR()

thoree/mut2 documentation built on June 11, 2025, 4:02 p.m.