run_thresholding_method: Run thresholding method

In timothy-barry/glmeiv: Implements the GLM-EIV model and method

Run thresholding method

Description

Runs the thresholding method on real data.

Usage

run_thresholding_method(
  phat,
  m,
  m_fam,
  m_offset,
  covariate_matrix,
  n_examples_per_param = 5,
  alpha = 0.95,
  exponentiate_coefs = TRUE
)

Arguments

phat	the binary vector of thresholded gRNA counts
m	mRNA counts
m_fam	family object describing mRNA counts
m_offset	offset for mRNA model
covariate_matrix	matrix of cell-specific covariates
n_examples_per_param	number of perturbed cells (per parameter) that must be present to attempt model fit
alpha	returns alpha-level CIs.

Details

Note: consider combining this function with run_thresholding_method_simulatr.

Value

data frame of fitted parameters and CIs.

timothy-barry/glmeiv documentation built on Jan. 30, 2024, 3:46 p.m.