HDX_ltseries_uptake_ratio: Calculate deuterioum uptake ration between the multiple time...
In tkostas/komics: Tools to analyze omics data

View source: R/HDX_ltseries_uptake_ratio.R

Calculate deuterioum uptake ratio between multiple time points over the last one, by dividing the uptake value from each timepoint with the last time point of the series. This division will be performed for each peptide of each protein.

1 2	HDX_ltseries_uptake_ratio(x, protein_col, peptide_col = "Sequence", uptake_col = "Uptake", time_col = "Exposure")

`x`	A dataframe with the input values.
`protein_col`	Name of the column containing the multiple proteins compared.
`peptide_col`	Name of the column containing the peptide sequence.
`uptake_col`	Name of the column containing the deuterium uptake values.
`time_col`	Name of the column containing the timepoint of the measurement.

x <- data
protein_col <- "mutant"
peptide_col <- "Sequence"
uptake_col <- "Uptake"
time_col <- "Exposure"

time_series_ratios <- HDX_ltseries_uptake_ratio(x = data, protein_col = "mutant")