refine_mappings: Refine pathway by cell type

Description Usage Arguments Value Examples

View source: R/refine_mappings.R

Description

Reduce the KEGG pathway by only including genes that are expressed within a given cell type

Usage

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refine_mappings(KEGG_mappings, cell_line)

Arguments

KEGG_mappings

The data.frame object generated by the function expand_KEGG_mappings

cell_line

Choose from the set of cell lines with baseline data; cell-lines may or may not have corresponding KO data

Value

A dataframe object with reduced set of pathway mappings to be passed on to other functions

Examples

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p53_KGML <- get_KGML("hsa04115")
p53_KEGG_mappings <-  expand_KEGG_mappings(p53_KGML)
MCF7_p53_mappings <- refine_mappings(p53_KEGG_mappings, "MCF7")

uc-bd2k/KEGGlincs documentation built on Dec. 8, 2017, 3:32 a.m.