guidematrix_to_triplet: Convert guide matrix into a dataframe containing cell,...

In weililab/scMAGeCK: Identify genes associated with multiple expression phenotypes in single-cell CRISPR screening data

Convert guide matrix into a dataframe containing cell, barcode, read and UMI count.

Description

Convert guide matrix into a dataframe, where columns include cell, barcode, read count and UMI count.

Usage

guidematrix_to_triplet(count_mat, RDS) 

Arguments

count_mat	A guide count matrix where columns are cell names and rows are guide names
RDS	A Seurat object or local RDS file path that contains the scRNA-seq dataset. Note that the dataset has to be normalized and scaled.

Value

A data frame that contains cell names, guide names, read count and UMI count as column.

weililab/scMAGeCK documentation built on April 21, 2024, 10:36 a.m.