PerformMetaMerge: Meta-Analysis Method: Direct merging of datasets
In xia-lab/MetaboAnalystR: An R Package for Comprehensive Analysis of Metabolomics Data
PerformMetaMerge R Documentation
Meta-Analysis Method: Direct merging of datasets
Description
This function is one of three methods to perform meta-analysis. Direct merging of individual data into
a mega-dataset results in an analysis of that mega-dataset as if the individual data were derived from the same experiment. This
method thereby ignores any inherent bias and heterogeneity between the different data. Because of this, there exists several confounders
such as different experimental protocols, technical platforms, and raw data processing procedures that can mask true underlying differences.
It is therefore highly suggested that this approach be used only when individual data are very similar (i.e. from the same lab, same platform,
without batch effects)."
Usage
PerformMetaMerge(mSetObj = NA, BHth = 0.05)
Arguments
mSetObj
Input name of the created mSet Object.
BHth
Numeric input to set the significance level. By default it is 0.05.
Author(s)
Jeff Xiajeff.xia@mcgill.ca
McGill University, Canada
License: GNU GPL (>= 2)
xia-lab/MetaboAnalystR documentation built on Dec. 23, 2024, 3:44 p.m.
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| PerformMetaMerge | R Documentation |
Meta-Analysis Method: Direct merging of datasets
Description
This function is one of three methods to perform meta-analysis. Direct merging of individual data into a mega-dataset results in an analysis of that mega-dataset as if the individual data were derived from the same experiment. This method thereby ignores any inherent bias and heterogeneity between the different data. Because of this, there exists several confounders such as different experimental protocols, technical platforms, and raw data processing procedures that can mask true underlying differences. It is therefore highly suggested that this approach be used only when individual data are very similar (i.e. from the same lab, same platform, without batch effects)."
Usage
PerformMetaMerge(mSetObj = NA, BHth = 0.05)
Arguments
mSetObj |
Input name of the created mSet Object. |
BHth |
Numeric input to set the significance level. By default it is 0.05. |
Author(s)
Jeff Xiajeff.xia@mcgill.ca McGill University, Canada License: GNU GPL (>= 2)
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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