NEWS.md

In zhuob/R4ClinicalTrial: R tools for clinical trials

r4ct 0.2.15

• add a wrapper function to read data more easily

r4ct 0.2.14

• Restructure the package such that only essential functions are included (removing simulation-related functions and shiny apps)
• add function get_tte_boundary for converting treatment effects of survival endpoint in different scales
• add function test_truncated_hochberg to perform truncated Hochberg testing

r4ct 0.2.11

• add function find_hazard for derivation of parameters for correlated ORR and OS
• add implementation of BOIN method for dose-escalation

r4ct 0.2.10

• add a function run_survival to run survival analysis

r4ct 0.2.9

• expand estimate_dlt_isoreg so that it can exclude dose levels with DU from estimating MTD. One du argument added

r4ct 0.2.8

• move function elements of mTPI2 from the packages to the app folder

r4ct 0.2.7

• update function estimate_dlt_isoreg with results verified by stats::isoreg
• expand the function estimate_dlt_isoreg so that it allows a cohort of size 0

r4ct 0.2.6

• fix a bug in the Farrington-Manning test
• Add test case

r4ct 0.2.5

• change the name to r4ct
• add functions for Farrington-Manning test method for non-inferiority test in the context of comparing two proportions

shinyapps4clinicaltrial 0.2.4

• Added a NEWS.md file to track changes to the package.

zhuob/R4ClinicalTrial documentation built on Feb. 4, 2025, 1:15 a.m.