heart.metaXcan: heart.metaXcan
In zhushijia/GIGSEA: Genotype Imputed Gene Set Enrichment Analysis

Description Usage Format Source

The MetaXcan-predicted differential gene expression from the cardiovascular disease (CVD) GWAS, CARDIoGRAMplusC4D (60,801 cases, 123,504 controls and 9.4M SNPs).

1	heart.metaXcan

A data frame with the following items:

gene: a gene's id
gene_name: a gene's name
zscore: MetaXcan's association result for the gene
effect_size: MetaXcan's association effect size for the gene
pvalue: P-value of the aforementioned statistic
pred_perf_r2: R2 of transcriptome prediction model's correlation to gene's measured transcriptome
pred_perf_pval: pval of transcriptome prediction model's correlation to gene's measured transcriptome
pred_perf_qval: qval of transcriptome prediction model's correlation to gene's measured transcriptome
n_snps_used: number of snps from GWAS that got used in MetaXcan analysis
n_snps_in_cov: number of snps in the covariance matrix
n_snps_in_model: number of snps in the prediction model
var_g: variance of the gene expression