Description Details Author(s) References Examples
A Poisson mixture model is implemented to identify differentially expressed genes from RNA-seq data.
Package: | HTSDiff |
Type: | Package |
Version: | 1.0.6 |
Date: | 2015-01-18 |
License: | GPL (>=3) |
LazyLoad: | yes |
Andrea Rau, Marie-Laure Martin-Magniette, Cathy Maugis-Rabusseau
Maintainer: Andrea Rau <andrea.rau@jouy.inra.fr>
S. Balzergue, G. Rigaill, V. Brunaud, E. Blondet, A. Rau, O. Rogier, J. Caius, C. Maugis-Rabusseau, L. Soubigou-Taconnat, S. Aubourg, C. Lurin, E. Delannoy, and M.-L. Martin-Magniette. (2014) HTSDiff: A Model-Based Clustering Alternative to Test-Based Methods in Differential Gene Expression Analyses by RNA-Seq Benchmarked on Real and Synthetic Datasets (submitted).
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## Generate synthetic data: 2000 genes under H0
test <- syntheticData(H0number = 2000)
## Mixture model differential analysis
## DEtest <- HTSDiff(test, c(1,1,2,2))
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