Sulfi: Pharmacokinetics of sulfisoxazole

Description Format Source Examples

Description

The Sulfi data frame has 12 rows and 2 columns from an experiment on the pharmacokinetics of sulfisoxazole.

Format

This data frame contains the following columns:

time

a numeric vector giving the time since drug administration (min).

conc

a numeric vector giving the observed concentration of sulfisoxazole (ug/ml).

Source

Bates and Watts (1998), Nonlinear Regression Analysis and Its Applications, Wiley (Appendix A1.5).

Examples

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fm1 <- nls(conc ~ SSbiexp(time, A1, lrc1, A2, lrc2), Sulfi)
coef(summary(fm1))
plotfit(fm1,
     xlab = "Time since drug administration (min)",
     ylab = expression("Sulfisoxazole concentration ("*mu*"g/ml)"))

NRAIA documentation built on May 31, 2017, 2:25 a.m.