Normalize total copy numbers by samples (total,fracB)

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Description

Normalize total copy numbers by samples (total,fracB), where total is the total (non-polymorphic) signal and fracB is the allele B fraction. It is only loci with a non-missing (NA) fracB value that are considered to be SNPs and normalized by NSA. The other loci are left untouched.

Usage

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## S3 method for class 'numeric'
sampleNByTotalAndFracB(data, references=NULL, ..., verbose=FALSE)

Arguments

data

An J numeric vector, where J is the number of loci for an specific sample.

references

An object specifying the normal regions of each sample.

...

Additional arguments passed to fitSNPsN.

verbose

See Verbose.

Value

Returns an Jx2 numeric array.