Mean simulation parameters obtained from the analysis of a real dataset
A data frame with 26408 observations on the following 3 variables.
a numeric vector with mean parameters for condition 1
a numeric vector with mean parameters for condition 2
a logical vector indicating which tags are differentially expressed (value 1)
Mean parameters provided in this package are empirical means (obtained after normalization for library size differences) of real data described in the following references.
Supplementary material of (Dillies et al., 2013) paper.
M.A. Dillies, A. Rau, J. Aubert, C. Hennequet-Antier, M. Jeanmougin, N. Servant, C. Keime, G. Marot, D. Castel, J. Estelle, G. Guernec, B. Jagla, L. Jouneau, D. Laloe, C. Le Gall, B. Schaeffer, S. Le Crom, M. Guedj and F. Jaffrezic, on behalf of the French StatOmique Consortium (2013) A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis. Briefings in Bioinformatics 14(6):671-83 .
T. Strub, S. Giuliano, T. Ye, et al. (2011) Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. emphOncogene 30:2319-32.