Description Details Author(s) References Examples
Routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics
Package: | npde |
Type: | Package |
Version: | 1.0 |
Date: | 2012-02-14 |
License: | GPL version 2 or later |
See the documentation for npde or autonpde for details
Emmanuelle Comets, Karl Brendel and France Mentre
Maintainer: Emmanuelle Comets <emmanuelle.comets@bichat.inserm.fr>
K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 | data(theopp)
data(simtheopp)
# Calling autonpde with dataframes
# x<-autonpde(theopp,simtheopp,1,3,4,boolsave=FALSE)
# x$npde
# Calling autonpde with names of files to be read from disk
# write.table(theopp,"theopp.tab",quote=FALSE,row.names=FALSE)
# write.table(simtheopp,"simtheopp.tab",quote=FALSE,row.names=FALSE)
# x<-autonpde(namobs="theopp.tab", namsim="simtheopp.tab", iid = 1, ix = 3, iy = 4, boolsave = FALSE)
# x$npde
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