npde-package: Normalised prediction distribution errors for nonlinear...

In npde: Normalised prediction distribution errors for nonlinear mixed-effect models

Description

Routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics

Details

Package:	npde
Type:	Package
Version:	1.0
Date:	2012-02-14
License:	GPL version 2 or later

See the documentation for npde or autonpde for details

Author(s)

Emmanuelle Comets, Karl Brendel and France Mentre

Maintainer: Emmanuelle Comets <[e-mail]>

References

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.

Examples

data(theopp)
data(simtheopp)

# Calling autonpde with dataframes

# x<-autonpde(theopp,simtheopp,1,3,4,boolsave=FALSE)
# x$npde

# Calling autonpde with names of files to be read from disk

# write.table(theopp,"theopp.tab",quote=FALSE,row.names=FALSE)
# write.table(simtheopp,"simtheopp.tab",quote=FALSE,row.names=FALSE)
# x<-autonpde(namobs="theopp.tab", namsim="simtheopp.tab", iid = 1, ix = 3, iy = 4, boolsave = FALSE)
# x$npde

npde documentation built on May 2, 2019, 5:23 p.m.