CODEX-package: A Normalization and Copy Number Variation Detection Method...
In CODEX: A Normalization and Copy Number Variation Detection Method for Whole Exome Sequencing
Description
CODEX is a normalization and copy number variation calling procedure for whole
exome DNA sequencing data. CODEX relies on the availability of multiple samples
processed using the same sequencing pipeline for normalization, and does not
require matched controls. The normalization model in CODEX includes terms that
specifically remove biases due to GC content, exon length and targeting and
amplification efficiency, and latent systemic artifacts. CODEX also includes a
Poisson likelihood-based recursive segmentation procedure that explicitly models
the count-based exome sequencing data.
Details
Package: CODEX
Type: Package
Version: 0.99.0
Date: 2015-01-13
License: GPL-2
CODEX takes as input the bam files/directories for whole exome sequencing
datasets and bed files for exonic positions, returns raw and normalized coverage
for each exon, and calls copy number variations with genotyping results.
Author(s)
Yuchao Jiang <yuchaoj@wharton.upenn.edu>, Nancy R. Zhang
CODEX documentation built on Nov. 8, 2020, 8:22 p.m.
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Description
CODEX is a normalization and copy number variation calling procedure for whole exome DNA sequencing data. CODEX relies on the availability of multiple samples processed using the same sequencing pipeline for normalization, and does not require matched controls. The normalization model in CODEX includes terms that specifically remove biases due to GC content, exon length and targeting and amplification efficiency, and latent systemic artifacts. CODEX also includes a Poisson likelihood-based recursive segmentation procedure that explicitly models the count-based exome sequencing data.
Details
| Package: | CODEX |
| Type: | Package |
| Version: | 0.99.0 |
| Date: | 2015-01-13 |
| License: | GPL-2 |
CODEX takes as input the bam files/directories for whole exome sequencing datasets and bed files for exonic positions, returns raw and normalized coverage for each exon, and calls copy number variations with genotyping results.
Author(s)
Yuchao Jiang <yuchaoj@wharton.upenn.edu>, Nancy R. Zhang
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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