CSAR: Statistical tools for the analysis of ChIP-seq data

Statistical tools for ChIP-seq data analysis. The package includes the statistical method described in Kaufmann et al. (2009) PLoS Biology: 7(4):e1000090. Briefly, Taking the average DNA fragment size subjected to sequencing into account, the software calculates genomic single-nucleotide read-enrichment values. After normalization, sample and control are compared using a test based on the Poisson distribution. Test statistic thresholds to control the false discovery rate are obtained through random permutation.

AuthorJose M Muino
Date of publicationNone
MaintainerJose M Muino <jose.muino@wur.nl>

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