Statistical tools for ChIP-seq data analysis. The package includes the statistical method described in Kaufmann et al. (2009) PLoS Biology: 7(4):e1000090. Briefly, Taking the average DNA fragment size subjected to sequencing into account, the software calculates genomic single-nucleotide read-enrichment values. After normalization, sample and control are compared using a test based on the Poisson distribution. Test statistic thresholds to control the false discovery rate are obtained through random permutation.
|Author||Jose M Muino|
|Bioconductor views||ChIPSeq Genetics Transcription|
|Maintainer||Jose M Muino <[email protected]>|
|Package repository||View on Bioconductor|
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