CNOlistToy2: Toy data with 2 time points

In CellNOptR: Training of boolean logic models of signalling networks using prior knowledge networks and perturbation data

Description

This data object contains the data associated with the Toy Model example from the package vignette, already loaded and formatted as a CNOlist object, and modified to contain 2 time points. The second time point is such a way that all of the signals stay as in time 1, except for cJun and Jnk which go to zero.

Usage

CNOlistToy

Format

CNOlistToy is a list with the fields "namesCues" (character vector), "namesStimuli" (character vector), "namesInhibitors" (character vector), "namesSignals" (character vector), "timeSignals" (numerical vector), "valueCues" (numerical matrix), "valueInhibitors" (numerical matrix), "valueStimuli"(numerical matrix), "valueSignals"(numerical matrix).

Source

This data and model is extracted from the Matlab version of CellNOpt1.0 (http://www.ebi.ac.uk/saezrodriguez/software.html#CellNetOptimizer).

References

J. Saez-Rodriguez, L. G. Alexopoulos, J. Epperlein, R. Samaga, D. A. Lauffenburger, S. Klamt and P. K. Sorger. Discrete logic modeling as a means to link protein signaling networks with functional analysis of mammalian signal transduction, Molecular Systems Biology, 5:331, 2009.

CellNOptR documentation built on Nov. 8, 2020, 6:58 p.m.