create_binaries: Defining the set of binary variables for the ILP...

In CellNOptR: Training of boolean logic models of signalling networks using prior knowledge networks and perturbation data

Description

This function takes as input the model and data in a CNOlist object in order to define the set of binary variablese.

Usage

create_binaries <- function(model, 
                            midas, 
                            numberOfExperiments, 
                            y_vector)

Arguments

model	the model
midas	the midas table
numberOfExperiments	the number of experimental conditions
y_vector	the variables for each interaction in the PKN

Author(s)

E Gjerga, H Koch

References

Alexander Mitsos, Ioannis N. Melas, Paraskeuas Siminelakis, Aikaterini D. Chairakaki, Julio Saez-Rodriguez, and Leonidas G. Alexopoulos. Identifying Drug Effects via Pathway Alterations using an Integer Linear Programming Optimization Formulation on Phosphoproteomic Data. PLoS Comput Biol. 2009 Dec; 5(12): e1000591.

CellNOptR documentation built on Nov. 8, 2020, 6:58 p.m.