DSS-package: Dispersion shrinkage for sequencing data
In DSS: Dispersion shrinkage for sequencing data
Description
DSS is an R library performing the differential expression analysis for
RNA-seq count data. Compared with other similar packages (DESeq,
edgeR), DSS implements a new dispersion shrinkage method to estimate the
gene-specific biological variance. Extensive simulation results
showed that DSS performs favorabily compared to DESeq and edgeR when
the variation of biological variances is large.
DSS only works for two group comparison at this time. We plan to
extend the functionalities and make it work for more general
experimental designs in the near future.
Author(s)
Hao Wu <hao.wu@emory.edu>
DSS documentation built on Nov. 8, 2020, 7:44 p.m.
R Package Documentation
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Description
DSS is an R library performing the differential expression analysis for RNA-seq count data. Compared with other similar packages (DESeq, edgeR), DSS implements a new dispersion shrinkage method to estimate the gene-specific biological variance. Extensive simulation results showed that DSS performs favorabily compared to DESeq and edgeR when the variation of biological variances is large.
DSS only works for two group comparison at this time. We plan to extend the functionalities and make it work for more general experimental designs in the near future.
Author(s)
Hao Wu <hao.wu@emory.edu>
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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