design: Experimental design for the example RRBS dataset
In DSS: Dispersion shrinkage for sequencing data

The RRBS dataset is from 16 samples with two factors (case and cell), each has two levels (so it's a 2x2 design).

1	data(RRBS)

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data(RRBS)
RRBS
design

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Loading required package: splines
An object of type 'BSseq' with
  5000 methylation loci
  16 samples
has not been smoothed
All assays are in-memory
   case cell
1    HC   rN
2    HC   rN
3    HC   rN
4   SLE   aN
5   SLE   rN
6   SLE   aN
7   SLE   rN
8   SLE   aN
9   SLE   rN
10  SLE   aN
11  SLE   rN
12   HC   aN
13   HC   aN
14   HC   aN
15   HC   aN
16   HC   rN