The Results of
interest() analysis in Intron-retention mode, for the
genes that feature U12-type introns and are located on Chr22 in MDS data.
An Object of class
SummarizedExperiment that contains intron retention
results generated by
interest() function on MDS data consisting of
bone-marrows samples of 8 MDS patients with ZRSR2 mutations, 4 patients without
the mutation and 4 healthy individuals.
A "DataFrame" (from "S4Vectors" package) that its rownames can be set as the sample identification names and the other columns are various annotations for the samples. Its column names are characters that describe the annotations.
List of size 2 that includes two numeric matrices:
counts that includes raw read counts of the sequencing reads
mapped to introns and exons, and (2)
scaledRetention, i.e. the
normalized read counts.
A NULL value.
A "DataFrame" (from "S4Vectors" package) that include intron and exon annotations.
A list of size 2 that includes parameter settings
Object of class
Madan, V., et.al., Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. Nat Communication 2015 Jan 14;6:6042. doi: 10.1038/ncomms7042.
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