MEDIPS was developed for analyzing data derived from methylated DNA immunoprecipitation (MeDIP) experiments followed by sequencing (MeDIP-seq). Nevertheless, several functionalities may be applied to other types of sequencing data (e.g. differential coverage or testing the saturation of ChIP-seq data). MEDIPS addresses several aspects in the context of MeDIP-seq data analysis including basic data processing, several quality controls, normalization, and identification of differential coverage.
Lukas Chavez, Matthias Lienhard, Joern Dietrich
Maintainer: Lukas Chavez <[email protected]>
Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmermann B, Lehrach H, Herwig R, Adjaye J., Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage, Genome Res. 2010 Oct;20(10):1441-50. Epub 2010 Aug 27.
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