MMAPPR2 maps mutations resulting from pooled RNA-seq data from the F2 cross of forward genetic screens. Its predecessor is described in a paper published in Genome Research (Hill et al. 2013). MMAPPR2 accepts aligned BAM files as well as a reference genome as input, identifies loci of high sequence disparity between the control and mutant RNA sequences, predicts variant effects using Ensembl's Variant Effect Predictor, and outputs a ranked list of candidate mutations.
|Author||Kyle Johnsen [aut], Nathaniel Jenkins [aut], Jonathon Hill [cre]|
|Bioconductor views||DNASeq PooledScreens RNASeq VariantDetection|
|Maintainer||Jonathon Hill <email@example.com>|
|Package repository||View on Bioconductor|
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