This package uses outlier statistics and gene set analysis to identify deregulated pathways.
The package applies three versions of outlier statistics across multiple molecular data types to create a single estimate at the gene level for the number of outliers relative to normal controls. These gene estimates are used in gene set analysis to determine deregulated pathways. Visualization of outlier calls provide sample specific information on potential drivers of the gene set statistic.
|License:||Gnu Public License|
Maintainer: Michael Ochs <email@example.com>
Ochs MF, Farrar JE, Considine M, Wei Y, Meschinchi S, Arceci RJ. Outlier analysis and top scoring pair for integrated data analysis and biomarker discovery. IEEE/ACM Trans Comput Biol and Bioinfo. 2014: 11: 520-32.