Description Usage Arguments Value Examples
Get information from individual slots in an MBR object and any available results from previous analysis.
1 2 | ## S4 method for signature 'MBR'
mbrGet(object, what = "status")
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object |
A preprocessed object of class MBR |
what |
a single character value specifying which information should be retrieved from the slots. Options: "TNI", "regulatoryElements", "dualRegulons", "results", "para", "summary", "status", "dualsCorrelation", "dualsOverlap", and "dualsCorMatrix" |
Content from slots in the MBR object
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 | ##--- load a dataset for demonstration
data("tniData", package = "RTN")
gexp <- tniData$expData
annot <- tniData$rowAnnotation
tfs <- c("IRF8","IRF1","PRDM1","E2F3","STAT4","LMO4","ZNF552")
##--- construct a tni object
rtni <- tni.constructor(gexp, regulatoryElements = tfs, rowAnnotation=annot)
##--- compute regulons
## set nPermutations>=1000
rtni <- tni.permutation(rtni, nPermutations=30)
## set nBootstrap>=100
rtni <- tni.bootstrap(rtni, nBootstrap=30)
## 'eps=NA' estimates threshold from empirical null
rtni <- tni.dpi.filter(rtni, eps=NA)
##--- construct a mbr object
rmbr <- tni2mbrPreprocess(rtni)
##--- get the 'TNI' slot using 'mbrGet'
tni <- mbrGet(rmbr, what="TNI")
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