combfunc: Combining two p-values using Fisher's product or normal...
In SPIA: Signaling Pathway Impact Analysis (SPIA) using combined evidence of pathway over-representation and unusual signaling perturbations

Description Usage Arguments Details Value Author(s) References See Also Examples

View source: R/combfunc.R

Combining two p-values using Fisher's product or normal inversion methods.

1	combfunc(p1=NULL,p2=NULL,combine="fisher")

`p1`	A vector of probabilities.
`p2`	A vector of probabilities.
`combine`	A string with the name of the method to be used. Options include "fisher","norminv"

Two vectors of p-values are combined into a vector of global p-values.

A vector of p-values.

Adi Laurentiu Tarca <atarca@med.wayne.edu>, Purvesh Khatri, Sorin Draghici

Adi L. Tarca, Sorin Draghici, Purvesh Khatri, et. al, A Signaling Pathway Impact Analysis for Microarray Experiments, 2008, Bioinformatics, 2009, 25(1):75-82.

spia

# Examples use colorectal cancer dataset
p1=c(0.2,0.4,0.1)
p2=c(0.01,0.7,0.01)
pG=combfunc(p1,p2,combine="fisher")
pG=combfunc(p1,p2,combine="norminv")