SpatialDecon: Deconvolution of mixed cells from spatial and/or bulk gene expression data

Using spatial or bulk gene expression data, estimates abundance of mixed cell types within each observation. Based on "Advances in mixed cell deconvolution enable quantification of cell types in spatially-resolved gene expression data", Danaher (2020). Designed for use with the NanoString GeoMx platform, but applicable to any gene expression data.

Package details

AuthorPatrick Danaher [aut, cre]
Bioconductor views FeatureExtraction GeneExpression ImmunoOncology Transcriptomics
MaintainerPatrick Danaher <pdanaher@nanostring.com>
LicenseGPL-3 + file LICENSE
Version1.0.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpatialDecon")

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SpatialDecon documentation built on Nov. 8, 2020, 6 p.m.