gscreend: Analysis of pooled genetic screens

Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.

README.md Vignette illustrating the usage of gscreend on simulated data

Vignettes Man pages API and functions Files

Package details
Author	Katharina Imkeller [cre, aut], Wolfgang Huber [aut]
Bioconductor views	CRISPR PooledScreens Software StatisticalMethod
Maintainer	Katharina Imkeller <k.imkeller@dkfz.de>
License	GPL-3
Version	1.4.0
URL	https://github.com/imkeller/gscreend
Package repository	View on Bioconductor
Installation	Install the latest version of this package by entering the following in R: `if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("gscreend")`