gscreend: Analysis of pooled genetic screens

Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The analysis of such screens is based on the comparison of gRNA abundances before and after a cell proliferation phase. The gscreend packages takes gRNA counts as input and allows detection of genes whose knockout decreases or increases cell proliferation.

Package details

AuthorKatharina Imkeller [cre, aut], Wolfgang Huber [aut]
Bioconductor views CRISPR PooledScreens Software StatisticalMethod
MaintainerKatharina Imkeller <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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gscreend documentation built on Nov. 8, 2020, 7:18 p.m.