edesignDR: Experimental design with different replicates

In maSigPro: Significant Gene Expression Profile Differences in Time Course Gene Expression Data

Description

edesignDR contains experimental set up of a replicated time course microarray experiment where rats were submitted to 3 different dosis of a toxic compound. A control and an placebo treatments are also present in the experiment.

Usage

data(edesignDR)

Format

A matrix with 54 rows and 7 columns

rows [1:54] "Array1" "Array2" "Array3" "Array4" ...

columns [1:7] "Time" "Replicates" "Control" "Placebo" "Low" "Medium" "High"

Details

Arrays are given in rows and experiment descriptors are given in columns. Row names contain array names.

"Time" indicates the values that variable Time takes in each hybridization.

"Replicates" is an index indicating replicate hyridizations, i.e. hybridizations are numbered, giving replicates the same number.

"Control", "Placebo", "Low", "Medium" and "High" columns indicate array assigment to experimental groups, coding with 1 and 0 whether each array belongs to that group or not.

References

Heijne, W.H.M.; Stierum, R.; Slijper, M.; van Bladeren P.J. and van Ommen B.(2003). Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach. Biochemical Pharmacology 65 857-875.

Examples

data(edesignDR)

maSigPro documentation built on Nov. 8, 2020, 6:51 p.m.