dot-methylcc_mstep: Maximization step
In methylCC: Estimate the cell composition of whole blood in DNA methylation samples
Description
Usage
Arguments
Value
Description
Maximization step in EM Algorithm for methylCC
Usage
1
.methylcc_mstep(Ys, Zs, current_pi_mle, current_theta, estep0, estep1)
Arguments
Ys
observed methylation levels in samples provided by user
of dimension R x n
Zs
Cell type specific regions of dimension R x K
current_pi_mle
cell composition MLE estimates of dimension K x n
current_theta
other parameter estimates in EM algorithm
estep0
Results from expectation step for unmethylated regions
estep1
Results from expectation step for methylated regions
Value
A list of the updated MLEs (or the M-Step
in the EM algorithm) used in .methylcc_engine()
methylCC documentation built on Nov. 8, 2020, 7:35 p.m.
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Description Usage Arguments Value
Description
Maximization step in EM Algorithm for methylCC
Usage
1 | .methylcc_mstep(Ys, Zs, current_pi_mle, current_theta, estep0, estep1)
|
Arguments
Ys |
observed methylation levels in samples provided by user of dimension R x n |
Zs |
Cell type specific regions of dimension R x K |
current_pi_mle |
cell composition MLE estimates of dimension K x n |
current_theta |
other parameter estimates in EM algorithm |
estep0 |
Results from expectation step for unmethylated regions |
estep1 |
Results from expectation step for methylated regions |
Value
A list of the updated MLEs (or the M-Step
in the EM algorithm) used in .methylcc_engine()
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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