dot-preprocess_estimatecc: .preprocess_estimatecc

In methylCC: Estimate the cell composition of whole blood in DNA methylation samples

Description

This function preprocesses the data before the estimatecc() function

Usage

.preprocess_estimatecc(object, verbose = TRUE,
  init_param_method = "random",
  celltype_specific_dmrs = celltype_specific_dmrs)

Arguments

object	an object can be a RGChannelSet, GenomicMethylSet or BSseq object
verbose	TRUE/FALSE argument specifying if verbose messages should be returned or not. Default is TRUE.
init_param_method	method to initialize parameter estimates. Choose between "random" (randomly sample) or "known_regions" (uses unmethyalted and methylated regions that were identified based on Reinus et al. (2012) cell sorted data.). Defaults to "random".
celltype_specific_dmrs	cell type specific differentially methylated regions (DMRs).

Value

A list of object to be used in estimatecc

methylCC documentation built on Nov. 8, 2020, 7:35 p.m.