perturbatr: Statistical Analysis of High-Throughput Genetic Perturbation Screens

perturbatr does stage-wise analysis of large-scale genetic perturbation screens for integrated data sets consisting of multiple screens. For multiple integrated perturbation screens a hierarchical model that considers the variance between different biological conditions is fitted. The resulting list of gene effects is then further extended using a network propagation algorithm to correct for false negatives.

Package details

AuthorSimon Dirmeier [aut, cre]
Bioconductor views CellBasedAssays ImmunoOncology Network Regression
MaintainerSimon Dirmeier <[email protected]>
Package repositoryView on Bioconductor
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perturbatr documentation built on May 6, 2019, 2:59 a.m.