prebs: Probe region expression estimation for RNA-seq data for improved microarray comparability

The prebs package aims at making RNA-sequencing (RNA-seq) data more comparable to microarray data. The comparability is achieved by summarizing sequencing-based expressions of probe regions using a modified version of RMA algorithm. The pipeline takes mapped reads in BAM format as an input and produces either gene expressions or original microarray probe set expressions as an output.

Package details

AuthorKarolis Uziela and Antti Honkela
Bioconductor views GeneExpression ImmunoOncology Microarray Preprocessing RNASeq Sequencing
MaintainerKarolis Uziela <karolis.uziela@scilifelab.se>
LicenseArtistic-2.0
Version1.30.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("prebs")

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prebs documentation built on Nov. 8, 2020, 5:40 p.m.