proBatch: Tools for Diagnostics and Corrections of Batch Effects in Proteomics

These tools facilitate batch effects analysis and correction in high-throughput experiments. It was developed primarily for mass-spectrometry proteomics (DIA/SWATH), but could also be applicable to most omic data with minor adaptations. The package contains functions for diagnostics (proteome/genome-wide and feature-level), correction (normalization and batch effects correction) and quality control. Non-linear fitting based approaches were also included to deal with complex, mass spectrometry-specific signal drifts.

Package details

AuthorJelena Cuklina <>, Chloe H. Lee <>, Patrick Pedrioli <>
Bioconductor views BatchEffect MassSpectrometry Normalization Preprocessing Proteomics QualityControl Software
MaintainerChloe H. Lee <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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proBatch documentation built on Nov. 8, 2020, 4:55 p.m.