Interactive R package with an intuitive Shiny-based graphical interface for alternative splicing quantification and integrative analyses of alternative splicing and gene expression based on The Cancer Genome Atlas (TCGA), the Genotype-Tissue Expression project (GTEx), Sequence Read Archive (SRA) and user-provided data. The tool interactively performs survival, dimensionality reduction and median- and variance-based differential splicing and gene expression analyses that benefit from the incorporation of clinical and molecular sample-associated features (such as tumour stage or survival). Interactive visual access to genomic mapping and functional annotation of selected alternative splicing events is also included.
|Author||Nuno Saraiva-Agostinho [aut, cre] (<https://orcid.org/0000-0002-5549-105X>), Nuno Luís Barbosa-Morais [aut, led, ths] (<https://orcid.org/0000-0002-1215-0538>), André Falcão [ths], Lina Gallego Paez [ctb], Marie Bordone [ctb], Teresa Maia [ctb], Mariana Ferreira [ctb], Ana Carolina Leote [ctb], Bernardo de Almeida [ctb]|
|Bioconductor views||AlternativeSplicing BiomedicalInformatics DifferentialExpression DifferentialSplicing GUI GeneExpression ImmunoOncology MultipleComparison PrincipalComponent RNASeq Sequencing Survival Transcription Transcriptomics Visualization|
|Maintainer||Nuno Saraiva-Agostinho <firstname.lastname@example.org>|
|License||MIT + file LICENSE|
|Package repository||View on Bioconductor|
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