Description Usage Arguments Value
Obtain the consensus null
1 2 3 4 5 6 7 8 9 10 11 12 13 | getG0(
statObs,
statsPerm,
z0Quant,
gridsize,
maxIter,
tol,
estP0args,
testPargs,
B,
p,
pi0
)
|
statObs |
A vector of lenght p with observed test statistics |
statsPerm |
A pxB matrix with permuation z-values |
z0Quant |
a vector of length of quantiles defining the central part R of the distribution. If a single number is supplied, then (z0quant, 1-z0quant) will be used |
gridsize |
An integer, the gridsize for the density estimation |
maxIter |
An integer, the maximum number of iterations in determining R |
tol |
The convergence tolerance. |
estP0args |
A list of arguments passed on to the estP0args() function |
testPargs |
A list of arguments passed on to quantileFun |
B |
an integer, the number of permutations |
p |
an integer, the number of hypotheses |
pi0 |
A known fraction of true null hypotheses. |
A list with following entries
PermDensFits |
The permutation density fits |
zSeq |
The support of the kernel for density estimation |
zValsDensObs |
The estimated densities of the observed z-values |
convergence |
A boolean, has the algorithm converged? |
weights |
Vector of length B with weights for the permutation distributions |
fdr |
Estimated local false discovery rate along the support of the kernel |
p0 |
The estimated fraction of true null hypotheses |
iter |
The number of iterations |
fitAll |
The consensus null fit |
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