wigToBigWig: Convert WIG to BigWig
In rtracklayer: R interface to genome annotation files and the UCSC genome browser

Description Usage Arguments Author(s) See Also

This function calls the Kent C library to efficiently convert a WIG file to a BigWig file, without loading the entire file into memory. This solves the problem where simple tools write out text WIG files, instead of more efficiently accessed binary BigWig files.

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wigToBigWig(x, seqinfo,
            dest = paste(file_path_sans_ext(x, TRUE), "bw", sep = "."),
            clip = FALSE)

`x`	Path or URL to the WIG file. Connections are not supported.
`seqinfo`	`Seqinfo` object, describing the genome of the data. All BigWig files must have this defined.
`dest`	The path to which to write the BigWig file. Defaults to `x` with the extension changed to “bw”.
`clip`	If `TRUE`, regions outside of `seqinfo` will be clipped, so that no error is thrown.