validation: validation

In scDD: Mixture modeling of single-cell RNA-seq data to identify genes with differential distributions

Description

Draw validation plots to show that the simulated dataset emulates characteristics of observed dataset.

Usage

validation(MV, DEIndex, Zeropercent_Base, Simulated_Data, numGenes)

Arguments

MV	Mean and Variance matrix for observed data
DEIndex	Index for genes chosen to be DE (can be NULL)
Zeropercent_Base	Zero percentage for corresponding gene expression values
Simulated_Data	Simulated dataset
numGenes	numeric value for the number of genes to simulate

Value

Validation plots

References

Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C. A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biology. 2016 Oct 25;17(1):222. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1077-y

scDD documentation built on Nov. 8, 2020, 7:10 p.m.