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A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.
Package details |
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Author | Daniel Greene, Sylvia Richardson and Ernest Turro |
Maintainer | Daniel Greene <dg333@cam.ac.uk> |
License | GPL (>= 2) |
Version | 5.10 |
Package repository | View on CRAN |
Installation |
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