CT: Meta-anaysis: noninvasive coronary angiography using computed...

CTR Documentation

Meta-anaysis: noninvasive coronary angiography using computed tomography (CT)

Description

CT for ruling out clinically significant coronary artery disease (CAD) in adults with suspected or known CAD. The accuracy and clinical value of CT was assessed in this meta-analysis.

MEDLINE, EMBASE, and ISI Web of Science searches from inception through 2 June 2009 and bibliographies of reviews. Prospective English- or German-language studies that compared CT or MRI with conventional coronary angiography in all patients and included sufficient data for compilation of 2 x 2 tables. Two investigators independently extracted patient and study characteristics; differences were resolved by consensus. 89 studies comprising 7516 assessed the diagnostic value of CT.

Usage

data("CT")

Format

A data frame consisting of 91 data sets (rows) and 10 attributes (columns)

Variable Names in order from left to right:

Author

Author


Year

Year


TP

true positive


FP

False positive


FN

False negative


TN

True negative


logitTPR

logit-true positive rate


logitTNR

logit-true negative rate


varlogitTPR

Variance of logit TPR


varlogitTNR

Variance of logit TPR


References

Schuetz GM, Zacharopoulou NM, Schlattmann P, Dewey M. Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging. Ann Intern Med. 2010 Feb 2;152(3):167-77. doi: 10.7326/0003-4819-152-3-201002020-00008.

Examples

#Use the EM-algorithm for a diagnostic meta-analysis based on a mixture 
#of bivariate  normal densities.
#Here fixed study specific variances are calculated based on logit 
#transformed sensitivity and specificity. 
data(CT)
p2 <- c(0.4,0.6)
lamlog12 <- c(2.93,3.22)
lamlog22 <- c(2.5,1.5)

m0 <- bivariate.EM(obs1=logitTPR,obs2=logitTNR,
                   var1=varlogitTPR,var2=varlogitTNR,
                   type="meta",lambda1=lamlog12,lambda2=lamlog22,
                   p=p2,data=CT,class="FALSE")

CAMAN documentation built on Sept. 22, 2023, 5:12 p.m.

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