CureRate-class: Class '"CureRate"'

In CR: Power Calculation for Weighted Log-Rank Tests in Cure Rate Models

Description

Class of objects like the output of function "curerate".

Objects from the Class

Objects can be created by calls of the form new("CureRate", ...).

Slots

cureobs:

Object of class "numeric"

medobs:

Object of class "numeric"

curerx:

Object of class "numeric"

medrx:

Object of class "numeric"

actime:

Object of class "vector"

futime:

Object of class "vector"

info:

Object of class "vector"

crits:

Object of class "vector"

alpha:

Object of class "numeric"

rho:

Object of class "numeric"

acrate:

Object of class "numeric"

probrx:

Object of class "numeric"

numreps:

Object of class "integer"

numobs:

Object of class "matrix"

timept:

Object of class "array"

deaths:

Object of class "array"

testname:

Object of class "character"

power:

Object of class "array"

beta:

Object of class "matrix"

indac:

Vector of objects of class "integer"

indfu:

Vector of objects of class "integer"

printflag:

Object of class "integer"

Methods

show

signature(object = "CureRate")

Author(s)

Emil A. Cornea, Bahjat F. Qaqish, and Joseph G. Ibrahim

Maintainer: Emil A. Cornea <[e-mail]>

See Also

curerate, show-methods, showcr

Examples

showClass("CureRate")

## Input Data
###############
# rho - specifies the value of rho in the G-rho test (Harrington and Fleming, 1982). 
# rho = 0 gives the logrank test, and rho = 1 the Peto-Peto Wilcoxon test
#(and rho = -1 the test discussed by Gray and Tsiatis, 1989).
rho = 0 

numreps = 500
##cureobs - probability of cure on the observation arm of the study
cureobs = .359
##curerx - probability of cure on the treatment arm of the study
curerx = .459
##medobs - median survival among the non-cured on observation
medobs = .747
##medrx - median survival among the non-cured on treatment
medrx = .859
##acrate - rate at which patients accrue, combined over both 
##observation and treatment arms of the study
acrate = 232
##probrx - probability of assignment to the treatment arm
probrx = .5
##actime  - accrual duration
actime = c(3.3, 3.5, 3.8); 
##futime  - followup duration
futime = c(2.0,  2.5) 
##info - vector of information times for the interim looks
##must be an increasing sequence in (0,1]
info = c( .35, .61, .86, 1.0)
##crits - vector of critical values corresponding to the 
##interim analysis time points specified in info
crits = c(3.6128, 2.6506, 2.1894, 2.0536)


##############################################################

### Log-rank test: rho=0 (default)
mycr<-curerate(rho ,numreps,cureobs,curerx,medobs,medrx,acrate,
          probrx,actime,futime,info,crits)
mycr       ### (*)

show(mycr)   ### same as above
showcr(mycr)   ### same as above
unclass(mycr)
showcr(mycr,full.results=TRUE)
showcr(mycr,indac=3,indfu=1)

CR documentation built on May 2, 2019, 7:22 a.m.