Description Usage Arguments Details Value References See Also Examples

Sensitivity and specificity, (positive and negative) predictive values and (positive and negative) diagnostic likelihood ratios of a two binary diagnostic tests in a paired study design.

1 | ```
acc.paired(tab, alpha, ...)
``` |

`tab` |
An object of class |

`alpha` |
Significance level alpha for 100(1-alpha)%-confidence intervals, the default is 0.05. |

`...` |
Additional arguments, usually not required. |

The calculation of accuracy measures and their variances follows standard methodology, e.g. described in Pepe (2003) or Zhou et al. (2011).

An list of class `acc.paired`

:

`Test1` |
A list of class |

`Test2` |
A list of class |

Pepe, M. (2003). The statistical evaluation of medical tests for classifcation and prediction. Oxford Statistical Science Series. Oxford University Press, 1st edition.

Zhou, X., Obuchowski, N., and McClish, D. (2011). Statistical Methods in Diagnostic Medicine. Wiley Series in Probability and Statistics. John Wiley & Sons, Hoboken, New Jersey, 2nd edition.

`tab.paired`

,
`print.acc.paired`

,
`acc.1test`

.

1 2 3 4 | ```
data(Paired1) # Hypothetical study data
b1 <- tab.paired(d=d, y1=y1, y2=y2, data=Paired1)
b2 <- acc.paired(b1)
print(b2)
``` |

```
Loading required package: gee
Loading required package: PropCIs
Diagnostic accuracy of test 'y1'
(Estimates, standard errors and 95%-confidence intervals)
Est. SE Lower CL Upper CL
Sensitivity 0.8802661 0.01528718 0.8503038 0.9102284
Specificity 0.6781609 0.02891782 0.6214830 0.7348388
PPV 0.8253638 0.01731081 0.7914353 0.8592924
NPV 0.7662338 0.02784617 0.7116563 0.8208113
Est. SE (log) Lower CL Upper CL
PDLR 2.7351124 0.0915147 2.2860079 3.2724472
NDLR 0.1765568 0.1346088 0.1356142 0.2298601
----------------------------------------------------------
Diagnostic accuracy of test 'y2'
(Estimates, standard errors and 95%-confidence intervals)
Est. SE Lower CL Upper CL
Sensitivity 0.7560976 0.02022128 0.7164646 0.7957305
Specificity 0.7969349 0.02490054 0.7481307 0.8457390
PPV 0.8654822 0.01718980 0.8317908 0.8991736
NPV 0.6540881 0.02667395 0.6018081 0.7063680
Est. SE (log) Lower CL Upper CL
PDLR 3.7234238 0.1255060 2.9114648 4.7618247
NDLR 0.3060507 0.0885996 0.2572629 0.3640906
```

DTComPair documentation built on May 29, 2017, 8:40 p.m.

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