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Implements escalation with overdose control (EWOC) trial designs using two drug combinations described by Tighiouart, Li and Rogatko (2017) <doi:10.1002/sim.6961>. It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.
Package details |
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Author | Quanlin Li and Mourad Tighiouart |
Maintainer | Quanlin Li <choplum@gmail.com> |
License | GPL (>= 2) |
Version | 1.0 |
Package repository | View on CRAN |
Installation |
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