EWOC2: Escalation with Overdose Control using 2 Drug Combinations

Implements escalation with overdose control (EWOC) trial designs using two drug combinations described by Tighiouart, Li and Rogatko (2017) <doi:10.1002/sim.6961>. It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.

Package details

AuthorQuanlin Li and Mourad Tighiouart
MaintainerQuanlin Li <[email protected]>
LicenseGPL (>= 2)
Version1.0
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("EWOC2")

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EWOC2 documentation built on May 2, 2019, 2:46 a.m.