Description Details Author(s) Examples
A collection of functions employed in environmental risk assessment to model exposure to a toxicant and predicting health effects, allowing to characterize variability and uncertainty in risk estimations
The DESCRIPTION file:
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~~ An overview of how to use the package, including the most important functions ~~
F. Barrio-Parra, with contributions from A. Dominguez-Castillo.
Maintainer: Fernando Barrio-Parra <fernando.barrio@upm.es>
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# Example of dermal contact with a chemical in swiming water
# Estimate the dermal absorbed dose during swiming in waters with a carcinogenic chemical
# (water concentration of 250 mg/m^3)
DWIR ( CW = 250)
# For a systemic effect:
DWIR ( CW= 250, AT=24*365)
# Specifying all the parameters for the carcinogenic case
I = DWIR ( CW=250, IR=1.5, EF = 300, ED = 24, BW = 85)
# Chemical Slope factor
SFAs = 1.5
# Dermal Absorption Factor
ABSAs = 3e-02
# Gastrointestinal Absorption Factor
GIAs = 1
# Risk Estimation
RISKdermal (AD = I, SF = SFAs, GI = GIAs)
#### Perform a test to assess the fitness of a theorical distribution to empirical data ####
set.seed(123)
a <- rnorm(n=100, mean =1.5, sd = 0.25)
b <- rnorm(n = 15, mean = 300, sd = 15)
fit_dist_test(a)
fit_dist_test(b)
# Graphical representation of data fitting to a distribution
plot_fit_dist(a, "norm")
plot_fit_dist(b, "norm")
#### Perform a Probabilistic Environmental Risk Assessment ####
Fita <- Fit_dist_parameter(a)
Fitb <- Fit_dist_parameter(b)
IRr <-random_number_generator(n = 10000, Fited = Fita,
dist = "norm", a =0.8, b = 2.1)
EFr <-random_number_generator(n = 10000, Fited = Fitb,
dist = "norm", a =250, b = 330)
I = DWIR ( CW=250, IR=IRr, EF = EFr, ED = 24, BW = 85)
# Risk Estimation
Risk <- RISKdermal (AD = I, SF = SFAs, GI = GIAs)
hist (Risk)
quantile (Risk, c (0.05, 0.25, 0.5, 0.75, 0.95))
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