getInfoLevelForChr: Compute the information level for a given chromosome after...

Description Usage Arguments Details Value Author(s) References See Also

Description

A function to compute the information proportions in a a given calibrated Hi-C matrix for a given chromosome. This will be the proportions of non-zero cells, representing information that was not discarded in the calibration step.

Usage

1
getInfoLevelForChr(calibHiC, hicCoord, chr)

Arguments

calibHiC

A calibrated Hi-C matrix. This matrix could be prepared with calibrate.

hicCoord

The genomic coordinates of the Hi-C bins. A data frame with the following mandatory columns: chr (chromosome name), start (start position), end (end position). Additional columns are permitted but will not be used.

chr

The name of the chromosome of interest (as it appears in hicCoord).

Details

The level of information can affect the accuracy of the 3D prediction, which may be lower for sparse calibration matrices (information level < 0.4).

Value

The information level for the given chromosome in the calibrated Hi-C matrix.

Author(s)

Yoli Shavit

References

Y. Shavit, F.K. Hamey, P. Lio', FisHiCal: an R package for iterative FISH-based calibration of Hi-C data, 2014 (submitted).

See Also

calibrate
lsmacof


FisHiCal documentation built on May 1, 2019, 10:09 p.m.